Motivation for breaking the hourglass
Inspired by the ‘ontogeny-phylogeny’ correlations and the hourglass model of evolutionary development, we recently asked whether we could break the hourglass or any TAI profile by extracting a stable set of genes, and gain information about the role these extracted genes have in the development of the organism.
Further motivation is in this thesis.
Break the hourglass using gaTAI
myTAI::destroy_pattern(example_phyex_set)…
This is a teaser.
The myTAI::destroy_pattern() requires the package
gataiR which is still under development.